Detalhe da pesquisa
1.
Characterization of RNA driven structural changes in full length RIG-I leading to its agonism or antagonism.
Nucleic Acids Res
; 51(17): 9356-9368, 2023 09 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37486777
2.
Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry Workflow.
Anal Chem
; 96(3): 1138-1146, 2024 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38165811
3.
Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg Med Chem Lett
; 84: 129193, 2023 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36822300
4.
High-throughput LC-MS method to investigate postprandial lipemia: considerations for future precision nutrition research.
Am J Physiol Endocrinol Metab
; 320(4): E702-E715, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33522396
5.
Direct Analysis from Phase-Separated Liquid Samples using ADE-OPI-MS: Applicability to High-Throughput Screening for Inhibitors of Diacylglycerol Acyltransferase 2.
Anal Chem
; 93(15): 6071-6079, 2021 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33819010
6.
Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.
Am J Physiol Endocrinol Metab
; 316(6): E1105-E1117, 2019 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30912961
7.
High-Throughput Bioassays using "Dip-and-Go" Multiplexed Electrospray Mass Spectrometry.
Angew Chem Int Ed Engl
; 58(49): 17594-17598, 2019 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31589796
8.
Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.
Am J Physiol Endocrinol Metab
; 315(3): E416-E424, 2018 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29509438
9.
Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
J Pharmacol Exp Ther
; 363(1): 80-91, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28724692
10.
Quantitation of wall teichoic acid in Staphylococcus aureus by direct measurement of monomeric units using LC-MS/MS.
Anal Biochem
; 518: 9-15, 2017 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27815077
11.
Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey.
J Lipid Res
; 57(12): 2150-2162, 2016 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27707816
12.
Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux.
J Lipid Res
; 57(3): 398-409, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26658238
13.
Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits.
Anal Bioanal Chem
; 408(1): 97-105, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26511226
14.
New methodologies for studying lipid synthesis and turnover: looking backwards to enable moving forwards.
Biochim Biophys Acta
; 1842(3): 402-13, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23707557
15.
Genome edited sheep and cattle.
Transgenic Res
; 24(1): 147-53, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25204701
16.
Highly efficient targeted chromosome deletions using CRISPR/Cas9.
Biotechnol Bioeng
; 112(5): 1060-4, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25362885
17.
Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors.
Bioorg Med Chem
; 23(3): 455-65, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25555732
18.
Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects.
Bioorg Med Chem Lett
; 24(2): 526-31, 2014 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24370012
19.
Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases.
Bioorg Med Chem Lett
; 24(2): 520-5, 2014 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24374272
20.
Lipidome of atherosclerotic plaques from hypercholesterolemic rabbits.
Int J Mol Sci
; 15(12): 23283-93, 2014 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25517033